Abstract:
This track aimed at retrieving protein evolutionary classification based on their surfaces meshes only. Given that proteins are dynamic, non-rigid objects and that evolution tends to conserve patterns related to their activity and function, this track offers a challenging issue using biologically relevant molecules. We evaluated the performance of 5 different algorithms and analysed their ability, over a dataset of 5,298 objects, to retrieve various conformations of identical proteins and various conformations of ortholog proteins (proteins from different organisms and showing the same activity).